Description

Water Soluble Carbodiimide is a versatile, zero-length crosslinking agent specifically engineered for aqueous reaction environments. This compound is critical for facilitating efficient amide bond formation between carboxylic acids and amines under mild, water-compatible conditions, eliminating the need for organic solvents. It is an essential reagent for researchers and manufacturers in bioconjugation, peptide synthesis, and the development of biomaterials and diagnostic assays.

Application

• Bioconjugation and Protein Modification: Crosslinking proteins, antibodies, or enzymes to other biomolecules, polymers, or solid surfaces for diagnostics and therapeutics.
• Peptide Synthesis: Acting as a coupling agent in solid-phase and solution-phase peptide synthesis in aqueous or mixed solvent systems.
• Hydrogel and Biomaterial Fabrication: Crosslinking water-soluble polymers (e.g., hyaluronic acid, chitosan, collagen) to create scaffolds for tissue engineering and drug delivery.
• Immunoassay Development: Conjugating haptens to carrier proteins or immobilizing antigens/antibodies onto microplates or sensor chips.
• Carbohydrate Chemistry: Facilitating the synthesis of glycoconjugates by linking sugars to proteins or other molecules.
• Polymer Chemistry: Modifying and crosslinking functional polymers in aqueous solutions for advanced material applications.

Basic Information

Item	Detail
Product Name	Water Soluble Carbodiimide
CAS No.	37147-07-2
Molecular Formula	C8H17N3O • HCl
Molecular Weight	207.70 g/mol (as hydrochloride salt)
Synonyms	1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide Hydrochloride; EDC Hydrochloride; EDAC; EDCI; WSC; WSCI; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl; N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide Hydrochloride
EINECS	253-354-1

Quality Control

Our Water Soluble Carbodiimide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity, identity, and performance consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, appearance, and solubility. We support compliance with cGMP and ISO standards for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive). For long-term stability, store under desiccant or inert atmosphere. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility (in Water)	Clear, colorless solution
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.