Description

Prolinomethyltetracycline CAS NO 37106-99-3 is a chemically modified tetracycline derivative, valued for its enhanced stability and targeted biological activity compared to its parent compound. This semi-synthetic antibiotic is engineered to address specific challenges in pharmaceutical research and development, offering a crucial tool for scientists. It is primarily required by the pharmaceutical industry for advanced antibiotic research, antimicrobial susceptibility testing, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: A key intermediate or reference standard in the synthesis and study of next-generation tetracycline-class antibiotics.
• Antimicrobial Susceptibility Testing (AST): Used in microbiological laboratories to study bacterial resistance mechanisms and evaluate the efficacy of antibiotic modifications.
• Biochemical Research: Employed to investigate protein synthesis inhibition and the specific interactions of tetracyclines with bacterial ribosomes.
• Veterinary Medicine Development: Explored for potential applications in creating advanced treatments for bacterial infections in animals.
• Academic & Institutional Studies: Serves as a critical reagent in university and research institute projects focused on medicinal chemistry and antibiotic discovery.

Basic Information

Product Name	Prolinomethyltetracycline
CAS No.	37106-99-3
Molecular Formula	C₂₈H₃₃N₃O₉
Molecular Weight	555.58 g/mol
Synonyms	N-[(4-Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido]methyl]pyrrolidine; Prolinomethyltetracycline; 7-Pyrrolidinomethyltetracycline; NSC 113029; PMT; Pyrrolidinomethyltetracycline
EINECS	Contact for details

Quality Control

Our Prolinomethyltetracycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.