Description

Dimethyl Pimelimidate is a bifunctional crosslinking agent belonging to the class of imido esters. This compound is valued for its ability to form stable covalent bonds with primary amines, making it a critical reagent in bioconjugation and protein chemistry. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors for applications requiring the stable linkage of biomolecules.

Application

• Protein-Protein Crosslinking: Used to create stable conjugates between antibodies, enzymes, and other proteins for diagnostic assays and therapeutic applications.
• Antibody-Drug Conjugate (ADC) Development: Serves as a linker molecule in the research and synthesis of targeted cancer therapies.
• Immobilization of Biomolecules: Facilitates the covalent attachment of proteins, peptides, or enzymes to solid supports like beads, plates, or membranes for biosensors and affinity chromatography.
• Structural Biology Studies: Employed to investigate protein structure, interactions, and complex formation through crosslinking mass spectrometry (XL-MS).
• Nucleic Acid Research: Can be used to conjugate oligonucleotides to carrier proteins or other molecules.
• Material Science: Applied in the surface modification of polymers and nanomaterials to introduce amine-reactive functional groups.

Basic Information

Product Name	Dimethyl Pimelimidate
CAS No.	36875-25-9
Molecular Formula	C9H16N2O4
Molecular Weight	216.24 g/mol
Synonyms	Dimethyl Pimelimidate Dihydrochloride; Pimelic Acid Dimethyl Ester Dihydrochloride; Dimethyl Heptanedioimidate Dihydrochloride; Pimelimidic Acid Dimethyl Ester Dihydrochloride; DMP; 1,7-Dimethyl Pimelimidate; NSC 112192; Heptanedioic acid, imido dimethyl ester, dihydrochloride
EINECS	Contact for details

Quality Control

Our Dimethyl Pimelimidate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for active content, to ensure it meets the high standards required for research and bioconjugation applications. Certificates of Analysis (COA) with detailed specifications and chromatograms are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.