Description

Isoapocodeine CAS NO 36507-69-4 is a specialized alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and analytical study of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies focused on neuropharmacology and medicinal chemistry. Its precise structure makes it a valuable tool for investigating structure-activity relationships and developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel opioid receptor modulators and other central nervous system (CNS) active compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related APIs and finished drug products.
• Medicinal Chemistry Research: Employed in academic and industrial R&D for studying metabolic pathways, pharmacokinetics, and the biochemical mechanisms of alkaloid derivatives.
• Process Development: Serves as a model compound for scaling up and optimizing synthetic routes in pilot plants and manufacturing settings.

Basic Information

Product Name	Isoapocodeine
CAS No.	36507-69-4
Molecular Formula	C₁₈H₂₁NO₃
Molecular Weight	299.37 g/mol
Synonyms	Isoapocodeine; 7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol; 6α-Hydroxy-3-methoxy-17-methyl-7,8-didehydro-4,5α-epoxymorphinan; Apocodeine isomer; Isoapocodein; 17-Methyl-6α-hydroxy-3-methoxy-7,8-didehydro-4,5α-epoxymorphinan
EINECS	Contact for details

Quality Control

Our Isoapocodeine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC and GC-MS. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.