Description

(12ξ)-13,19-Didehydro-15,20-Dihydro-8,12-Dihydroxy-4-Methyl-11,16-Dioxosenecionan-4-Ium CAS NO 36506-81-7 is a complex pyrrolizidine alkaloid derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the study of natural product chemistry and targeted therapeutics. It serves as a key building block for medicinal chemists and research institutions focused on oncology, neurology, and metabolic disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for research into anti-cancer and anti-inflammatory agents.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate enzyme inhibition and receptor binding mechanisms.
• Natural Product Synthesis: A key chiral synthon for the total or semi-synthesis of complex natural products and their analogs for structure-activity relationship (SAR) studies.
• Academic & Discovery Chemistry: Employed in university and industrial R&D labs for exploring new chemical entities and developing new synthetic methodologies.
• High-Value Fine Chemical Production: Integrated into multi-step synthesis processes for producing specialized, high-potency compounds in milligram to kilogram scales.

Basic Information

Product Name	(12ξ)-13,19-Didehydro-15,20-Dihydro-8,12-Dihydroxy-4-Methyl-11,16-Dioxosenecionan-4-Ium
CAS No.	36506-81-7
Molecular Formula	C18H25NO6+
Molecular Weight	351.40 g/mol (for cation)
Synonyms	13,19-Didehydro-15,20-dihydro-8,12-dihydroxy-4-methyl-11,16-dioxosenecionan-4-ium; Senecionan-4-ium, 13,19-didehydro-15,20-dihydro-8,12-dihydroxy-4-methyl-11,16-dioxo-, (12ξ)-; Pyrrolizidine alkaloid derivative; PA intermediate; 4-Methylsenecionan-4-ium derivative; (12ξ)-4-Methyl-11,16-dioxosenecionan-4-ium
EINECS	Contact for details

Quality Control

Our production of (12ξ)-13,19-Didehydro-15,20-Dihydro-8,12-Dihydroxy-4-Methyl-11,16-Dioxosenecionan-4-Ium adheres to stringent quality management protocols. Each batch is characterized and purified using advanced chromatographic techniques to ensure high chemical and isomeric purity, critical for research reproducibility. Comprehensive analytical data, including NMR, HPLC, and MS, is provided. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.