Description

N(1)-((5'-Phosphoribulosyl)Formimino)-5-Aminoimidazo-4-Carboxamide Ribonucleotide is a key biochemical intermediate in the histidine biosynthesis pathway. This compound matters for its critical role in enzymatic research and as a reference standard for metabolic studies. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in amino acid metabolism, pathway analysis, and inhibitor screening.

Application

• Biochemical Research: Essential intermediate for studying the histidine biosynthesis pathway in microorganisms and plants.
• Enzymology Studies: Used as a substrate or reference compound for investigating the enzyme imidazole glycerol phosphate synthase (HisFH complex).
• Metabolite Analysis: Serves as a high-purity analytical standard for LC-MS or HPLC quantification in metabolic profiling.
• Pharmaceutical Development: Potential building block or target for developing antimicrobial agents that disrupt bacterial histidine production.
• Diagnostic Reagent Manufacturing: Used in the formulation of specialized kits for enzymatic assays and metabolic disorder diagnostics.
• Academic Reference Material: Supplied to universities and research labs for educational and investigative purposes in biochemistry.

Basic Information

Item	Details
Product Name	N(1)-((5'-Phosphoribulosyl)Formimino)-5-Aminoimidazo-4-Carboxamide Ribonucleotide
CAS No.	36244-86-7
Molecular Formula	C14H23N6O15P2
Molecular Weight	576.31 g/mol
Synonyms	ProFAR; N1-[(5'-Phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide ribonucleotide; (5'-Phosphoribulosyl)formimino-AICAR-P; 5'-Phosphoribulosylformimino-5-aminoimidazole-4-carboxamide ribonucleotide; 1-(5-Phospho-D-ribulosylformimino)-5-amino-1H-imidazole-4-carboxamide ribonucleotide; HisH Reaction Intermediate; Histidine Biosynthesis Intermediate; Imidazole glycerol phosphate synthase substrate
EINECS	Contact for details

Quality Control

Our N(1)-((5'-Phosphoribulosyl)Formimino)-5-Aminoimidazo-4-Carboxamide Ribonucleotide is produced under stringent conditions suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to ensure compliance with your specific research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.