Description

Mg(II) Protoporphyrin IX Dipotassium Salt is a high-purity metalloporphyrin complex, a key biochemical intermediate derived from chlorophyll and heme biosynthesis pathways. This compound is valued for its role as a potent inhibitor of heme oxygenase, making it a critical research tool in studying oxidative stress, cellular metabolism, and porphyria-related disorders. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors for biochemical research, diagnostic assay development, and as a reference standard.

Application

• Biochemical Research: Used as a specific and potent inhibitor of heme oxygenase (HO) enzymes (HO-1 and HO-2) in cellular and molecular biology studies.
• Pharmaceutical Development: Serves as a reference standard and key intermediate in drug discovery programs targeting oxidative stress, inflammation, and neurodegenerative diseases.
• Diagnostic Reagents: Employed in the formulation of specialized reagents and kits for clinical diagnostics and research assays related to heme metabolism.
• Enzyme Studies: Acts as a substrate analog and inhibitor in enzymatic studies to elucidate the mechanisms of heme degradation and iron recycling pathways.
• Photodynamic Therapy (PDT) Research: Investigated for its photosensitizing properties in preclinical research for potential applications in cancer therapy.
• Academic & Industrial R&D: Essential for universities, contract research organizations (CROs), and biotech companies conducting fundamental research on porphyrin chemistry and biology.

Basic Information

Product Name	Mg(II) Protoporphyrin IX Dipotassium Salt
CAS No.	35979-27-2
Molecular Formula	C34H32MgN4O4 • 2K
Molecular Weight	671.15 g/mol (for free acid, contact for salt form details)
Synonyms	Magnesium Protoporphyrin IX Dipotassium Salt; Mg-Protoporphyrin IX K2 Salt; MgPP(IX) Dipotassium; Heme Oxygenase Inhibitor; 13,17-Bis(2-carboxyethyl)-3,8-divinyl-2,7,12,18-tetramethylporphyrin-21,23-diide, magnesium(2+), dipotassium salt; Protoporphyrin IX Magnesium Dipotassium Salt; Mg-Deuteroporphyrin IX Dipotassium Salt (common name)
EINECS	Contact for details

Quality Control

Our Mg(II) Protoporphyrin IX Dipotassium Salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as HPLC purity, identity confirmation by UV-Vis and mass spectrometry, and residual solvent analysis is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Dark purple to brownish powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Characteristic Soret band ~410-420 nm
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Heavy Metals	≤ 20 ppm
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.