Description

n-Acetylpsychosine is a chemically modified derivative of psychosine (galactosylsphingosine), a key intermediate in sphingolipid metabolism. This compound is of significant interest in biochemical and pharmaceutical research for its role in studying lysosomal storage disorders and sphingolipid signaling pathways. It serves as a critical reference standard and research tool for scientists in academic institutions, pharmaceutical R&D, and diagnostic laboratories focused on lipid biology and disease mechanisms.

Application

• Biomedical Research: Used as a reference standard and analytical tool in studies of sphingolipid metabolism, particularly related to Krabbe disease (globoid cell leukodystrophy).
• Pharmaceutical Development: Serves as a key intermediate or biomarker in the research and development of therapies for lysosomal storage disorders.
• Diagnostic Assays: Employed as a calibrant or control in the development of LC-MS/MS or other analytical methods for quantifying psychosine and related lipids in biological samples.
• Enzymology Studies: Utilized as a substrate or inhibitor in enzymatic assays to study the activity of galactocerebrosidase and other relevant enzymes.
• Cell Biology: Applied in cell culture models to investigate the cytotoxic effects of lysosphingolipids and their role in neuroinflammation and demyelination.
• Metabolomics: Acts as a defined metabolite in lipidomic profiling to understand disease states and identify potential therapeutic targets.

Basic Information

Product Name	n-Acetylpsychosine
CAS No.	35823-61-1
Molecular Formula	C26H49NO8
Molecular Weight	503.68 g/mol
Synonyms	N-Acetylpsychosine; N-Acetyl-galactosylsphingosine; 1-O-(β-D-Galactopyranosyl)-N-acetyl-2-amino-1,3-octadecanediol; Galactosyl-N-acetylsphingosine; D-erythro-N-Acetylpsychosine; N-Acetyl-D-erythro-sphingosine galactoside; N-Acetyl-galactosyl-sphingosine; N-Acetyl-galactocerebroside sphingosine
EINECS	Contact for details

Quality Control

Our n-Acetylpsychosine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including chromatographic purity and structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (Mass Spec)	Conforms (M+Na)+
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.