Description

Fmoc-Gly-Gly-Oh CAS NO 35665-38-4 is a high-purity, protected dipeptide building block essential for solid-phase peptide synthesis (SPPS). Its core value lies in providing a reliable and efficient means to incorporate a glycine-glycine sequence into growing peptide chains under standard Fmoc-chemistry conditions. This compound is critically needed by research institutions, pharmaceutical developers, and CROs engaged in the discovery and production of novel therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key dipeptide fragment for the controlled elongation of peptide backbones using Fmoc/t-Bu protection strategies.
• Pharmaceutical Intermediate: In the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Probe Development: For creating labeled peptides, peptide-drug conjugates, or affinity tags for biochemical studies.
• Combinatorial Chemistry Libraries: As a building block for generating diverse peptide libraries for high-throughput screening.
• Academic & Industrial Research: Used in laboratories studying protein-protein interactions, enzyme substrates, or receptor ligands.
• Custom Peptide Service Providers: A fundamental raw material for companies offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Gly-Gly-Oh
CAS No.	35665-38-4
Molecular Formula	C19H18N2O5
Molecular Weight	354.36 g/mol
Synonyms	Fmoc-Gly-Gly-OH; N-(9-Fluorenylmethoxycarbonyl)glycylglycine; Fmoc-Gly-Gly; Glycylglycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; N-Fmoc-glycylglycine; (9H-Fluoren-9-ylmethoxy)carbonyl-glycyl-glycine; Fmoc-GG-OH; N-α-Fmoc-glycylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-Gly-Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.