Description

Methyl Bisnorbiotinyl Ketone is a specialized biochemical intermediate derived from biotin, a vital B-complex vitamin. This compound matters for its role as a key building block in the synthesis of advanced biotin derivatives and biotinylated probes used in life science research and diagnostic applications. It is primarily needed by manufacturers in the pharmaceutical, nutraceutical, and biotechnology sectors for developing high-purity active ingredients and research reagents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel biotin-based active pharmaceutical ingredients (APIs) and drug conjugates.
• Bioconjugation Reagent: Used for the preparation of biotinylated molecules, enabling applications in affinity chromatography, immunoassays, and diagnostic kits.
• Biochemical Research: Acts as a versatile intermediate in academic and industrial research for studying vitamin metabolism and enzyme cofactors.
• Nutraceutical Development: Employed in the development of advanced vitamin supplements and specialized nutritional formulations.
• Probe Synthesis: Utilized to create labeled probes for molecular biology techniques, including blotting and detection systems.

Basic Information

Product Name	Methyl Bisnorbiotinyl Ketone
CAS No.	35638-35-8
Molecular Formula	C13H20N2O3S
Molecular Weight	284.38 g/mol
Synonyms	Methyl 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic Acid Methyl Ester; Methyl 5-[(3aS,4S,6aR)-2-Oxohexahydrothieno[3,4-d]imidazol-4-yl]pentanoate; Bisnorbiotin Methyl Ester; Methyl Bisnorbiotinate; Biotin Methyl Ester Derivative
EINECS	Contact for details

Quality Control

Our Methyl Bisnorbiotinyl Ketone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.