Description

(3β,16E)-16,17,18,19-Tetradehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester CAS NO 35467-43-7 is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate or reference standard for the development of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in the exploration of new therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or building block in the discovery and development of new drug candidates, particularly those targeting neurological or other specialized pathways.
• Reference Standard for Analytical Chemistry: Used as a high-purity standard in HPLC, LC-MS, and NMR for method development, validation, and quality control in research and manufacturing settings.
• Academic & Institutional Research: Employed in universities and research institutes for studying structure-activity relationships (SAR), synthetic methodology, and the chemical biology of indole alkaloids.
• Process Chemistry & Scale-Up: Acts as a starting material or intermediate for process chemists working on the optimization and pilot-scale synthesis of complex organic molecules.
• Biochemical Tool Compound: Potentially used in vitro or in vivo studies to investigate specific biological mechanisms and interactions at a molecular level.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and client-specific projects.

Basic Information

Product Name	(3β,16E)-16,17,18,19-Tetradehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester
CAS No.	35467-43-7
Molecular Formula	C22H24N2O3
Molecular Weight	364.44 g/mol
Synonyms	Methyl (3β,16E)-16,17,18,19-tetradehydro-17-methoxycorynan-16-carboxylate; 17-Methoxy-16,17-didehydro-16E-corynan-16-carboxylic acid methyl ester; 16,17-Didehydro-17-methoxycorynan-16-carboxylic acid methyl ester; (16E)-17-Methoxy-16,17-didehydrocorynan-16-carboxylic acid methyl ester; Methyl 17-methoxy-16,17-didehydrocorynan-16-carboxylate; Alkaloid C-Compound Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (3β,16E)-16,17,18,19-Tetradehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC-MS, NMR, and IR spectroscopy to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere at 2-8°C to maximize stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade) ≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.