Description

1-Octadecanoyl-2-[(Cis,Cis,Cis,Cis)-5,8,11,14-Eicosatetraenoyl]-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid of significant interest in advanced biochemical and pharmaceutical research. This compound serves as a critical component for constructing model membranes and liposomal drug delivery systems, enabling the study of lipid-protein interactions and cellular processes. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic companies working on targeted therapeutics, biomarker discovery, and advanced formulation science.

Application

• Liposome and Nanoparticle Formulation: A key structural lipid for creating stable, functional liposomes used in drug delivery, particularly for encapsulating hydrophobic or sensitive active pharmaceutical ingredients (APIs).
• Biomembrane Research: Essential for constructing artificial cell membranes and lipid bilayers to study membrane fluidity, protein insertion, and signal transduction mechanisms in vitro.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in lipid-based drug product manufacturing.
• Biochemical Assay Development: Used as a substrate or matrix in enzymatic assays, fluorescence studies, and other diagnostic platforms investigating phospholipase activity or lipid metabolism.
• Nutraceutical and Cosmeceutical R&D: Investigated for its potential role in advanced skincare formulations and bioactive supplement delivery systems due to its biomimetic properties.

Basic Information

Product Name	1-Octadecanoyl-2-[(Cis,Cis,Cis,Cis)-5,8,11,14-Eicosatetraenoyl]-Sn-Glycero-3-Phosphocholine
CAS No.	35418-59-8
Molecular Formula	C46H84NO8P
Molecular Weight	810.14 g/mol
Synonyms	18:0-20:4 PC; 1-Stearoyl-2-Arachidonoyl-sn-Glycero-3-Phosphocholine; SAPC; SAAPC; Phosphatidylcholine (18:0/20:4(5Z,8Z,11Z,14Z)); 1-Octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; L-α-Phosphatidylcholine, 1-stearoyl-2-arachidonoyl-; Arachidonoyl Stearoyl Phosphatidylcholine
EINECS	Contact for details

Quality Control

Every batch of our 1-Octadecanoyl-2-[(Cis,Cis,Cis,Cis)-5,8,11,14-Eicosatetraenoyl]-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and specific tests is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (argon or nitrogen). This product is hygroscopic and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation and oxidative degradation. Once opened, purge the container with inert gas and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, ethanol; forms liposomes in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.