Description

2,3-Dihexadecanoyl-Sn-Glycero-1-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine with two identical palmitoyl chains. This compound is a critical building block for creating biomimetic membranes and liposomal delivery systems, offering superior batch-to-batch consistency for research and formulation. It is essential for scientists and manufacturers in advanced pharmaceutical development, particularly for drug delivery, vaccine adjuvants, and membrane biophysics research.

Application

• Liposome and Nanoparticle Formulation: A primary component for constructing stable, uniform liposomes used in drug and gene delivery systems.
• Biomembrane Research: Used to create model lipid bilayers (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and fusion.
• Vaccine Adjuvant Development: Serves as a key lipid in the development of next-generation lipid-based adjuvants to enhance immune response.
• Diagnostic Reagents: Incorporated into diagnostic kits and assays that utilize membrane-based detection mechanisms.
• Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a skin-identical lipid for enhancing barrier function and active ingredient delivery.
• Cell Culture & Cryopreservation: Acts as a supplement in specialized cell culture media and as a protective agent in cryopreservation solutions.

Basic Information

Product Name	2,3-Dihexadecanoyl-Sn-Glycero-1-Phosphocholine
CAS No.	35418-55-4
Molecular Formula	C40H80NO8P
Molecular Weight	734.03 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine; DPPC; 1,2-Dipalmitoylphosphatidylcholine; L-α-Phosphatidylcholine, dipalmitoyl; Palmitoylphosphatidylcholine; Lecithin, dipalmitoyl; 3-sn-Phosphatidylcholine, 1,2-dihexadecanoyl; Cardiolipin analog (precursor)
EINECS	Contact for details

Quality Control

Our 2,3-Dihexadecanoyl-Sn-Glycero-1-Phosphocholine is manufactured under strict quality systems suitable for pharmaceutical research and development. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate at -20°C. The material is hygroscopic and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.