Description

Gelsemine Hydrochloride is a high-purity alkaloid salt derived from the *Gelsemium* species, valued for its specific biological activity and structural significance. This compound serves as a critical reference standard and research chemical in pharmacological and phytochemical studies. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and analytical testing facilities for method development and biological screening.

Application

• Pharmacological Research: Used as a reference standard in studies investigating neuroactive alkaloids and their mechanisms of action.
• Analytical Chemistry: Serves as a certified standard for HPLC, LC-MS, and other chromatographic methods for quality control of botanical extracts.
• Phytochemical Studies: Employed in the isolation, identification, and quantification of alkaloids from natural product sources.
• Biochemical Assays: Utilized as a precise reagent in receptor-binding studies and other in vitro bioassays.
• Pharmaceutical Development: Acts as a key intermediate or starting material in the synthesis of novel chemical entities for drug discovery programs.
• Academic Teaching: Provides a high-purity example of a complex plant alkaloid for advanced chemistry and pharmacology courses.

Basic Information

Product Name	Gelsemine Hydrochloride
CAS No.	35306-33-3
Molecular Formula	C20H26N2O3·HCl
Molecular Weight	378.89 g/mol
Synonyms	Gelsemine HCl; Gelsemine Monohydrochloride; (19Z)-Gelsemine Hydrochloride; 2,7-Didehydro-3,17-dideoxy-19,20α-epoxy-1α-hydroxycuran-16-carboxylic Acid Methyl Ester Hydrochloride; 16-Carbomethoxy-19(Z)-gelsemine Hydrochloride; NSC 177386; Gelsemium Alkaloid Hydrochloride
EINECS	Contact for details

Quality Control

Our Gelsemine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support research and development with materials suitable for use as analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.