Description

4-Epioxytetracycline is a key chemical intermediate and derivative of the oxytetracycline class of antibiotics. This compound is essential for research and development in the pharmaceutical sector, particularly for studying antibiotic structure-activity relationships and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis and structural modification of tetracycline-class antibiotics.
• Biochemical Studies: Used as a reference standard or probe in studies investigating bacterial protein synthesis inhibition and antibiotic resistance mechanisms.
• Fine Chemical Synthesis: Acts as a building block for the preparation of more complex, specialized tetracycline derivatives with potential enhanced properties.
• Analytical Standard: Employed as a high-purity standard in analytical methods (e.g., HPLC, LC-MS) for quality control and regulatory testing of related pharmaceutical products.
• Academic Research: Utilized in university and institutional labs for chemical, pharmacological, and microbiological research projects.

Basic Information

Product Name	4-Epioxytetracycline
CAS No.	35259-39-3
Molecular Formula	C₂₂H₂₄N₂O₉
Molecular Weight	460.44 g/mol
Synonyms	4-Epioxytetracycline; 4-Epi-oxytetracycline; 4-Epioxyteracycline; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,5,6,10,11,12a-hexahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; Oxytetracycline 4-epimer
EINECS	Contact for details

Quality Control

Our 4-Epioxytetracycline is manufactured and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from methods including HPLC, IR, and loss on drying. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable material for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.