Description

Sceletium A4 is a specific alkaloid compound derived from the *Sceletium tortuosum* plant, also known as kanna. This product, identified by CAS No. 35135-35-4, is valued for its high purity and consistent quality, making it a critical reference standard and active ingredient for research and development. It is primarily sought by the pharmaceutical, nutraceutical, and botanical extract industries for applications in analytical chemistry, product formulation, and pharmacological studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of kanna extracts and related products in quality control laboratories.
• Nutraceutical Formulation: Serves as a key active ingredient or marker compound in the development of standardized dietary supplements and herbal formulations targeting mood support.
• Biochemical Research: Employed in academic and industrial research to study the pharmacological properties, mechanism of action, and metabolic pathways of mesembrine-type alkaloids.
• Analytical Method Development: Essential for developing and validating analytical methods such as HPLC, LC-MS, and GC-MS for the accurate quantification of alkaloids in complex matrices.
• Botanical Extract Standardization: Used to calibrate and standardize commercial *Sceletium tortuosum* extracts to ensure consistent potency and meet label claims.

Basic Information

Product Name	Sceletium A4
CAS No.	35135-35-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Mesembrenone; 4'-O-Demethylmesembrenone; Sceletium Alkaloid A4; (3aR,4S,7aS)-4-[(4-Hydroxyphenyl)methyl]-3a,4,7,7a-tetrahydro-1H-indole-6,7-diol; Kanna Alkaloid A4
EINECS	Contact for details

Quality Control

Our Sceletium A4 is produced and tested under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the stringent requirements for reference standards and high-grade ingredients. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.