Description

1,3,5[10]-Estratriene-3,17-Diol-6-One 6-[o-Carboxymethyl]Oxime is a chemically modified steroid derivative, specifically an oxime conjugate of an estradiol-related structure. This compound is a critical high-purity intermediate for advanced pharmaceutical synthesis and biochemical research. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or precursor in studies involving estrogen receptors and metabolic pathways.
• Diagnostic Reagent Development: Serves as a hapten for the production of antibodies in immunoassay kits.
• Academic & Institutional R&D: Employed in universities and research institutes for investigating steroid chemistry and biochemistry.
• Fine Chemical Synthesis: A specialized intermediate for creating custom steroidal compounds with targeted modifications.

Basic Information

Product Name	1,3,5[10]-Estratriene-3,17-Diol-6-One 6-[o-Carboxymethyl]Oxime
CAS No.	35048-47-6
Molecular Formula	C20H25NO5
Molecular Weight	359.42 g/mol
Synonyms	6-Carboxymethoxyiminoestradiol; Estra-1,3,5(10)-triene-3,17-diol-6-one 6-(O-carboxymethyl)oxime; 6-(Carboxymethoxylmino)estra-1,3,5(10)-triene-3,17-diol; 6-CMO-Estradiol; 6-CMO-E2; Estradiol-6-CMO; 17β-Estradiol 6-(O-carboxymethyl)oxime
EINECS	Contact for details

Quality Control

Our 1,3,5[10]-Estratriene-3,17-Diol-6-One 6-[o-Carboxymethyl]Oxime is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.