Description

N(Sup 1)-Acetylspermidine Dihydrochloride is a high-purity, chemically modified derivative of the natural polyamine spermidine. This compound serves as a critical biochemical tool and research standard for studying polyamine metabolism, cellular signaling, and aging-related pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on life science, oncology, and neurobiology.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic assays to study spermidine/spermine N1-acetyltransferase (SSAT) activity and polyamine catabolism.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the development of therapeutics targeting polyamine pathways in cancer, neurodegenerative diseases, and metabolic disorders.
• Diagnostic Reagents: Employed in the formulation of calibration kits and reagents for clinical diagnostics and research ELISA kits measuring polyamine levels.
• Cell Culture & Physiology Studies: Applied in *in vitro* studies to investigate the role of acetylated polyamines in cell proliferation, apoptosis, and response to oxidative stress.
• Metabolomics & Analytical Chemistry: Acts as a certified reference material (CRM) for accurate quantification in LC-MS, GC-MS, and HPLC analyses of biological samples.

Basic Information

Product Name	N(Sup 1)-Acetylspermidine Dihydrochloride
CAS No.	34450-16-3
Molecular Formula	C9H23Cl2N3O
Molecular Weight	260.21 g/mol
Synonyms	N1-Acetylspermidine Dihydrochloride; N-Acetylspermidine Dihydrochloride; Monoacetylspermidine Dihydrochloride; Spermidine, N1-acetyl-, dihydrochloride; 1-Acetylspermidine Dihydrochloride; N-(3-Aminopropyl)-N-(4-aminobutyl)acetamide Dihydrochloride
EINECS	Contact for details

Quality Control

Our N(Sup 1)-Acetylspermidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) with lot-specific data are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.