Description

[13As,(-)]-5,8,13,13A-Tetrahydro-2,10,11-Trimethoxy-6H-Dibenzo[A,G]Quinolizine-1-Ol is a high-purity, complex heterocyclic alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and a key intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of potential therapeutic agents targeting neurological and cardiovascular systems.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and screening new drug candidates with potential biological activity.
• Asymmetric Synthesis: Employed in stereoselective reactions due to its defined chiral centers, facilitating the construction of enantiomerically pure compounds.
• Biochemical Research: Investigated for its interaction with biological targets, such as enzymes or receptors, in biochemical assays.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, natural product chemistry, and chemical biology.

Basic Information

Product Name	[13As,(-)]-5,8,13,13A-Tetrahydro-2,10,11-Trimethoxy-6H-Dibenzo[A,G]Quinolizine-1-Ol
CAS No.	34413-12-2
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	(-)-Corypalmine; (13aS)-5,8,13,13a-Tetrahydro-2,10,11-trimethoxy-6H-dibenzo[a,g]quinolizin-1-ol; L-Corypalmine; (S)-Corypalmine; 1-Hydroxy-2,10,11-trimethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline; NSC 158399; BRN 0091162
EINECS	Contact for details

Quality Control

Our [13As,(-)]-5,8,13,13A-Tetrahydro-2,10,11-Trimethoxy-6H-Dibenzo[A,G]Quinolizine-1-Ol is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and chiral purity, and is accompanied by a detailed Certificate of Analysis (COA) available upon request. We support research and development with material that meets exacting standards for identity, purity, and composition.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.