Description

1-Methyladenosine Hydroiodide is a chemically modified nucleoside derivative, specifically the hydroiodide salt of 1-methyladenosine. This compound is of significant value in biochemical and pharmaceutical research as a stable, crystalline form for studying RNA modification pathways and enzyme mechanisms. It serves as a critical reference standard and synthetic intermediate for researchers and manufacturers in the fields of nucleoside chemistry, antiviral drug development, and epigenetics.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of RNA methylation, adenosine deaminases, and other nucleoside-modifying enzymes.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Diagnostic Reagent Development: Employed in the formulation of calibration standards for analytical methods like HPLC and LC-MS used in metabolomics and therapeutic drug monitoring.
• Enzymology Studies: Acts as a specific inhibitor or analog in mechanistic studies of purine metabolism and signaling pathways.
• Academic & Industrial R&D: Essential for basic research in molecular biology and for process development in fine chemical synthesis.

Basic Information

Item	Details
Product Name	1-Methyladenosine Hydroiodide
CAS No.	34308-25-3
Molecular Formula	C11H16IN5O4
Molecular Weight	409.18 g/mol
Synonyms	1-Methyladenosine Hydroiodide; 1-Methyladenosine HI; 1-Methyladenosine Iodide; N1-Methyladenosine Hydroiodide; 6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-1-ium Iodide; 1-Methyladenosine, hydroiodide; Adenosine, 1-methyl-, hydroiodide
EINECS	Contact for details

Quality Control

Our 1-Methyladenosine Hydroiodide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.