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n-Oleoyl-D-Erythro-Sphinganine CAS NO 34227-83-3
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CAS No.:34227-83-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Oleoyl-D-Erythro-Sphinganine is a high-purity, synthetic sphingolipid derivative, specifically a ceramide precursor. This compound is of significant value in advanced biochemical research and pharmaceutical development due to its role in modulating cellular signaling pathways related to apoptosis, differentiation, and stress responses. It is primarily needed by researchers and manufacturers in the life sciences, particularly those focused on lipidomics, drug discovery for metabolic and inflammatory diseases, and the formulation of high-end cosmetic actives targeting skin barrier function.
Application
- Biochemical Research: A critical standard and reagent for studying sphingolipid metabolism, ceramide synthesis pathways, and their role in cell signaling.
- Pharmaceutical Development: Used as a reference compound and potential intermediate in the discovery of novel therapeutics targeting cancer, neurodegenerative disorders, and metabolic syndromes.
- Cosmetic Science: Serves as a key ingredient or model compound in the development of premium skincare formulations aimed at enhancing epidermal barrier repair and moisture retention.
- Lipidomics & Analytical Standards: Employed as a certified reference material (CRM) for the accurate quantification and identification of complex sphingolipids in biological samples via LC-MS/MS.
- Cell Culture & In Vitro Studies: Utilized to investigate the effects of specific ceramide species on cellular behavior, proliferation, and response to external stimuli.
Basic Information
| Product Name | n-Oleoyl-D-Erythro-Sphinganine |
| CAS No. | 34227-83-3 |
| Molecular Formula | C₃₆H₇₁NO₃ |
| Molecular Weight | 565.96 g/mol |
| Synonyms | N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]octadec-9-enamide; Ceramide(d18:0/18:1(9Z)); D-erythro-C18 Ceramide (d18:0/18:1(9Z)); N-Oleoylsphinganine; (2S,3R,4E)-2-Octadecanoylamino-4-octadecene-1,3-diol (related isomer); C18-Ceramide (d18:0/18:1); Sphinganine, N-oleoyl-; N-(Oleoyl)-sphinganine |
| EINECS | Contact for details |
Quality Control
Our n-Oleoyl-D-Erythro-Sphinganine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry and NMR, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Specific Rotation | Contact for details |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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