Description

4-Methylumbelliferyl p-Trimethylammonium Cinnamate Chloride is a specialized fluorogenic substrate and a key biochemical reagent. This compound is critical for the sensitive detection and quantification of enzyme activity, particularly for cholinesterases and other esterases. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic industries for high-throughput screening and assay development.

Application

• Enzyme Activity Assays: A primary fluorogenic substrate for the detection and kinetic study of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
• High-Throughput Screening (HTS): Used in pharmaceutical research to screen for potential inhibitors or activators of cholinesterase enzymes.
• Diagnostic Reagent Development: Serves as a core component in developing sensitive diagnostic kits for neurological conditions and organophosphate exposure.
• Biochemical Research: Employed in mechanistic studies of esterase function and in the development of novel fluorometric detection methods.
• Toxicology Testing: Applied in environmental and clinical toxicology to assess the effects of pesticides, nerve agents, and other cholinesterase-targeting compounds.

Basic Information

Product Name	4-Methylumbelliferyl p-Trimethylammonium Cinnamate Chloride
CAS No.	34197-47-2
Molecular Formula	C23H24ClNO5
Molecular Weight	429.90 g/mol
Synonyms	4-MU-TMA-Cinnamate Chloride; 4-Methylumbelliferyl (4-Trimethylammonio)cinnamate Chloride; MUTMAC; Fluorogenic Acetylcholinesterase Substrate; AChE Fluorogenic Substrate; 7-Hydroxy-4-methylcoumarin-6-yl 4-(trimethylammonio)cinnamate chloride; 4-Methylumbelliferyl-6-(4-trimethylammoniocinnamate) Chloride
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl p-Trimethylammonium Cinnamate Chloride is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Fluorogenic Activity	Functional in standard AChE assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.