Description

30-Deoxynigericin Sodium Salt is a potent polyether ionophore compound derived from nigericin, specifically engineered for enhanced research utility. This sodium salt form offers improved solubility and stability, making it a critical tool for studying ion transport across biological membranes and its role in cellular processes. It is primarily utilized by researchers in biochemistry, pharmacology, and cell biology for investigating mitochondrial function, apoptosis, and as a model ionophore in bioenergetics studies.

Application

• Biochemical Research: A key tool for studying potassium/proton antiport activity and disrupting ion gradients across lipid membranes.
• Mitochondrial Studies: Used to investigate mitochondrial membrane potential, uncoupling of oxidative phosphorylation, and induction of apoptosis.
• Cell Biology: Employed as a model ionophore to explore cellular ion homeostasis, signal transduction, and cell death pathways.
• Antimicrobial Research: Serves as a reference compound in studies of polyether antibiotics and their mechanisms of action against pathogens.
• Pharmacology: Utilized in drug discovery and development for screening compounds that modulate ion transport or mitochondrial function.
• Academic & Industrial R&D: Essential for basic research and applied projects in biotechnology and pharmaceutical development.

Basic Information

Product Name	30-Deoxynigericin Sodium Salt
CAS No.	34052-60-3
Molecular Formula	C40H67O11Na
Molecular Weight	746.94 g/mol
Synonyms	30-Deoxynigericin Na Salt; NSC 381474; Nigericin analog, 30-deoxy-; Sodium 30-deoxynigericinate; 30-Deoxy-nigericin sodium; Polyether antibiotic ionophore; K+/H+ antiporter inhibitor
EINECS	Contact for details

Quality Control

Our 30-Deoxynigericin Sodium Salt is produced under stringent quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 1.0%
Solubility	Soluble in DMSO, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.