Description

1,7-Dimethyluric Acid is a dimethylated derivative of uric acid, serving as a key intermediate and reference standard in biochemical and pharmaceutical research. Its defined structure makes it valuable for studying purine metabolism and for the synthesis of more complex xanthine derivatives. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic pathway analysis, analytical method development, and high-purity chemical synthesis.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant and control material in analytical methods (e.g., HPLC, LC-MS) for drug metabolism and pharmacokinetic (DMPK) studies.
• Biochemical Research: Serves as a specific substrate or inhibitor in enzymatic studies related to xanthine oxidase and other purine metabolic pathways.
• Metabolite Synthesis: Acts as a crucial synthetic intermediate for the preparation of more complex methylxanthines and related purine-based compounds.
• Diagnostic Reagent Manufacturing: Employed in the formulation of diagnostic kits and assays designed to detect and quantify purine derivatives in biological samples.
• Academic Research: Utilized in universities and research labs for fundamental studies on uric acid chemistry, crystallization, and solubility properties.
• Quality Control: Applied as an internal standard in quality control laboratories to ensure the purity and consistency of pharmaceutical products containing xanthine analogs.

Basic Information

Product Name	1,7-Dimethyluric Acid
CAS No.	33868-03-0
Molecular Formula	C7H8N4O3
Molecular Weight	196.16 g/mol
Synonyms	1,7-Dimethyluric Acid; 1,7-Dimethyl-1H,3H,7H-purine-2,6,8-trione; 1,7-Dimethyl-2,6,8-trioxopurine; Uric Acid, 1,7-Dimethyl-; Theacrine (Note: Theacrine is a closely related tetramethyluric acid, but this name is sometimes associated in searches); 1,7-Dimethyl-3,7-dihydro-1H-purine-2,6,8-trione
EINECS	Contact for details

Quality Control

Our 1,7-Dimethyluric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification (IR), purity assay (HPLC), and control of related substances, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.