Description

Prolyl-Leucyl-Glycine is a synthetic tripeptide composed of the amino acids proline, leucine, and glycine. This compound is of significant interest in biochemical and pharmaceutical research due to its potential role as a peptide fragment and its utility in studying enzyme-substrate interactions. It serves as a key intermediate and reference standard for researchers and manufacturers in the life sciences sector. The product is supplied as a high-purity material suitable for laboratory and development applications.

Application

• Biochemical Research: Used as a model peptide substrate for studying protease and peptidase enzyme kinetics and specificity.
• Pharmaceutical Development: Serves as a key intermediate or building block in the synthesis of more complex peptide-based drug candidates.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in peptide analysis (e.g., HPLC, MS).
• Neuroscience Studies: Investigated for potential biological activity related to neuropeptide metabolism and signaling pathways.
• Cosmetic Peptide Research: Explored as a potential active ingredient or precursor in the development of cosmetic formulations targeting skin health.
• Academic & Institutional Labs: Utilized in university and research institute settings for fundamental studies in peptide chemistry and molecular biology.

Basic Information

Product Name	Prolyl-Leucyl-Glycine
CAS No.	33676-42-5
Molecular Formula	C16H28N4O4
Molecular Weight	340.42 g/mol
Synonyms	PLG; Pro-Leu-Gly; Pro-Leu-Gly-OH; L-Prolyl-L-leucylglycine; L-Pro-L-Leu-Gly; H-Pro-Leu-Gly-OH; 2-[(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxopentan-2-yl]amino]-4-methylpentanoyl]pyrrolidin-2-yl]acetic acid
EINECS	Contact for details

Quality Control

Our Prolyl-Leucyl-Glycine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including identification by spectroscopic methods and purity assessment by chromatographic techniques. Certificates of Analysis (COA) detailing specific results for identity, assay, and impurities are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.