Description

(3ξ,16R)-2α,5α-Epoxy-1,2-Dihydro-12-Methoxy-17-Oxoakuammilan-16-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and a valuable reference standard for the development of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in neurological and anti-inflammatory drug discovery.
• Reference Standard: Used as a high-purity analytical standard for quality control, method development, and identification in HPLC, LC-MS, and NMR analyses.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the biological activity of akuammilan alkaloid derivatives.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for the total synthesis of complex natural products and novel heterocyclic compounds.
• Biochemical Research: Utilized in studies investigating alkaloid biosynthesis pathways and enzyme mechanisms.

Basic Information

Product Name	(3ξ,16R)-2α,5α-Epoxy-1,2-Dihydro-12-Methoxy-17-Oxoakuammilan-16-Carboxylic Acid Methyl Ester
CAS No.	33023-09-5
Molecular Formula	C22H26N2O6
Molecular Weight	414.45 g/mol
Synonyms	Methyl (3ξ,16R)-2α,5α-epoxy-1,2-dihydro-12-methoxy-17-oxoakuammilan-16-carboxylate; 17-Oxoakuammilan-16-carboxylic acid, 1,2-dihydro-12-methoxy-2,5-epoxy-, methyl ester, (2α,3ξ,5α,16R)-; Akuammilan alkaloid derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (3ξ,16R)-2α,5α-Epoxy-1,2-Dihydro-12-Methoxy-17-Oxoakuammilan-16-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.