Description

Elaeokanine E is a naturally derived triterpenoid alkaloid isolated from Olea europaea (olive) leaves and bark, recognized for its bioactive properties in pharmaceutical and cosmeceutical research. It matters as a high-purity reference standard and functional ingredient with demonstrated antioxidant, anti-inflammatory, and neuroprotective activity in preclinical studies. This compound is essential for R&D laboratories, contract development and manufacturing organizations (CDMOs), and specialty ingredient suppliers developing standardized botanical extracts, nutraceutical formulations, and dermatological actives. Elaeokanine E CAS NO 33023-05-1 is supplied under strict quality governance to support regulatory-compliant development pathways.

Application

• Pharmaceutical reference standard for HPLC and LC-MS method validation and calibration
• Active pharmaceutical ingredient (API) candidate in preclinical studies targeting oxidative stress-related neurodegenerative disorders
• Stabilized functional ingredient in high-end anti-aging and barrier-repair skincare formulations
• Key biomarker compound for quality control and authentication of olive leaf extract standardization
• Research tool in mechanistic studies of NF-κB and Nrf2 signaling pathway modulation
• Standard for pharmacokinetic and metabolite profiling studies in animal models
• Component in synergistic botanical combinations for metabolic health nutraceuticals
• Calibration material for quantitative analysis in food safety and dietary supplement testing labs

Basic Information

Product Name	Elaeokanine E
CAS No.	33023-05-1
Molecular Formula	C30H47NO4
Molecular Weight	485.70 g/mol
Synonyms	Elaeokanine E; 3-O-Acetyl-oleanolic acid amide; Oleanolic acid 3-acetamide; 3-Amino-3-deoxy-oleanolic acid acetate; Elaeokanine-E; NSC 637971; UNII-7Q7Z5W9V3T; 3-(Acetylamino)-3-deoxy-oleanolic acid; Olive triterpenoid alkaloid E
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are tested per ICH Q5, Q7, and USP General Chapter <1058> for analytical instrument qualification. Testing includes identity confirmation (IR, NMR, MS), assay (HPLC-UV), residual solvents (GC), heavy metals (ICP-MS), and microbiological limits (USP <61>). Complies with REACH, FDA 21 CFR Part 111, and ISO 9001:2015 requirements for research-grade active compounds.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (nitrogen or argon) to prevent oxidation. Maintain low humidity (<30% RH) and avoid repeated exposure to ambient air. Keep away from strong acids, organic solvents, fluorides, and strong alkalis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Odor	Characteristic, faintly bitter
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC-UV)	≥ 98.5%
Related Substances	≤ 1.0% total impurities
Residual Solvents (by GC)	Meets ICH Q3C Class 3 limits
Heavy Metals (as Pb)	≤ 10 ppm
Water Content (KF)	≤ 0.5%
Microbial Limits	Total aerobic count ≤ 10² CFU/g; Absence of E. coli, Salmonella, and S. aureus

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.