Description

Glycohyocholic Acid is a conjugated bile acid, specifically the glycine conjugate of hyocholic acid, which plays a significant role in lipid metabolism and emulsification. This high-purity biochemical is essential for research and development in metabolic studies and pharmaceutical applications. It serves as a critical reference standard and intermediate for scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent industries.

Application

• Pharmaceutical Research & Development: As a key reference standard for analytical method development and validation in bile acid metabolism studies.
• Biochemical Reagent: Used in enzymatic assays and as a substrate or inhibitor in studies of metabolic pathways and liver function.
• Diagnostic Kit Manufacturing: A vital component in the calibration and quality control of diagnostic kits for liver and gastrointestinal disorders.
• Academic & Clinical Research: For investigating cholestasis, liver diseases, and the role of conjugated bile acids in digestion and signaling.
• Metabolite Standard: Essential for quantitative analysis in LC-MS, HPLC, and GC-MS platforms in metabolomics and pharmacokinetic studies.
• Precursor for Derivatives: Serves as a starting material for the synthesis of more complex bile acid analogs and labeled compounds for tracer studies.

Basic Information

Product Name	Glycohyocholic Acid
CAS No.	32747-08-3
Molecular Formula	C₂₆H₄₃NO₆
Molecular Weight	465.63 g/mol
Synonyms	N-[(3α,5β,6α)-3,6,12-Trihydroxy-24-oxocholan-24-yl]glycine; Glycohyocholate; 3α,6α,12α-Trihydroxy-5β-cholan-24-oyl Glycine; Hyocholic Acid Glycine Conjugate; Glycine Hyocholate; N-(3α,6α,12α-Trihydroxy-5β-cholan-24-oyl)glycine
EINECS	Contact for details

Quality Control

Every batch of Glycohyocholic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for each lot, detailing results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with the standards expected for high-value biochemical and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Optical Rotation	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.