Description

(S)-(-)-2-Bromopropionic Acid is a high-purity chiral building block essential for the synthesis of optically active compounds. Its value lies in its role as a versatile intermediate for introducing the propionate moiety with defined stereochemistry into target molecules. This product is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutics.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptide Modification: Employed to introduce bromoalkyl side chains into peptides and peptide mimetics for structure-activity relationship (SAR) studies.
• Polymer Science: Monomer for creating functionalized polymers with specific chiral centers or reactive bromo-handles for further modification.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new asymmetric synthetic methodologies and novel compound libraries.

Basic Information

Product Name	(S)-(-)-2-Bromopropionic Acid
CAS No.	32644-15-8
Molecular Formula	C₃H₅BrO₂
Molecular Weight	152.98 g/mol
Synonyms	(S)-2-Bromopropanoic Acid; (S)-α-Bromopropionic Acid; L-2-Bromopropionic Acid; (-)-2-Bromopropionic Acid; (S)-(-)-2-Bromopropanoic Acid; (2S)-2-Bromopropanoic Acid; Propanoic acid, 2-bromo-, (2S)-; (S)-2-Bromopropionsäure (German)
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Bromopropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for research and production use. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]₂₀D	-20° to -24° (c=1 in ethanol)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.