Description

Cholic acid is a primary bile acid, a key biochemical synthesized in the liver from cholesterol. It is an essential biochemical intermediate and solubilizing agent, critical for the emulsification and absorption of dietary fats and fat-soluble vitamins in the intestine. This high-purity compound is vital for manufacturers in the pharmaceutical, research, and fine chemical sectors, where it serves as a crucial starting material for drug synthesis, a reference standard in analytical laboratories, and a component in specialized formulations.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Biochemical Research: Used as a critical reagent in studies of liver function, cholesterol metabolism, and gastrointestinal physiology.
• Reference Standard: Serves as a high-purity analytical standard in HPLC, LC-MS, and other quality control methods for pharmaceutical and diagnostic applications.
• Cell Culture & Microbiology: Employed as a supplement in certain specialized cell culture media and in studies of bacterial metabolism in the gut.
• Fine Chemical Synthesis: Utilized as a chiral building block or surfactant in the synthesis of complex organic molecules and specialty chemicals.

Basic Information

Product Name	Cholic Acid
CAS No.	32500-01-9
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid; Cholate; Cholic Acid (8CI); 5β-Cholan-24-oic Acid-3α,7α,12α-triol; Gallogen; Colalin; 1-Cholic Acid; 3,7,12-Trihydroxycholanic Acid
EINECS	251-074-9

Quality Control

Our Cholic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR), to ensure it meets the stringent requirements of pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	+36° to +38° (c=1, in ethanol)
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.