Description

(S)-(+)-2-Hydroxypropyl p-Toluenesulfonate is a high-purity chiral building block and alkylating agent, essential for the synthesis of enantiomerically pure compounds. Its value lies in its ability to introduce the (S)-2-hydroxypropyl moiety with high stereochemical fidelity, enabling the production of advanced intermediates for pharmaceuticals and fine chemicals. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as an alkylating agent in stereoselective reactions to construct complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific chirality.
• Agrochemical Research: Serves as a building block for developing chiral herbicides, fungicides, and plant growth regulators.
• Academic & R&D Laboratories: Utilized in methodological development and discovery chemistry for novel synthetic pathways.
• Material Science: Potential precursor for chiral polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	(S)-(+)-2-Hydroxypropyl p-Toluenesulfonate
CAS No.	32464-98-5
Molecular Formula	C10H14O4S
Molecular Weight	230.28 g/mol
Synonyms	(S)-(+)-1-(p-Toluenesulfonyloxy)-2-propanol; (S)-1-(4-Methylphenylsulfonyloxy)propan-2-ol; (S)-2-Hydroxypropyl Tosylate; (S)-HPT; (S)-2-Propanol, 1-(4-methylbenzenesulfonate); (S)-1-Tosyloxy-2-propanol; (S)-Methyl-p-toluenesulfonyloxyethanol; (S)-α-Methyl-β-tosyloxyethanol
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Hydroxypropyl p-Toluenesulfonate is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]D20	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.