Description

1,2-Diphytanoylphosphatidylcholine is a synthetic, chemically defined phospholipid featuring two saturated, branched phytanoyl chains. This unique structure provides exceptional stability against oxidation and hydrolysis, making it a critical component for creating robust, long-lasting lipid-based systems. It is essential for researchers and manufacturers in advanced pharmaceutical development, particularly for formulating next-generation lipid nanoparticles (LNPs) and model membrane systems where precise control and reproducibility are paramount.

Application

• Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for mRNA, siRNA, and other nucleic acid delivery systems, enhancing particle stability and delivery efficiency.
• Model Membrane Studies: Used in biophysical research to create stable, well-defined planar bilayers, liposomes, and supported lipid bilayers (SLBs) for studying membrane protein interactions.
• Drug Delivery Vehicles: A component in liposomal and other nano-carrier formulations for targeted and sustained release of active pharmaceutical ingredients (APIs).
• Biomimetic Coatings: Employed to create stable, biocompatible surface coatings for medical devices and biosensors.
• Reconstitution of Membrane Proteins: Provides a stable, native-like lipid environment for the functional study of integral membrane proteins.
• Reference Standard: Serves as a high-purity analytical standard in lipidomics and quality control laboratories.

Basic Information

Item	Details
Product Name	1,2-Diphytanoylphosphatidylcholine
CAS No.	32448-32-1
Molecular Formula	C52H104NO8P
Molecular Weight	902.35 g/mol
Synonyms	DPhyPC; 1,2-Diphytanoyl-sn-glycero-3-phosphocholine; Diphytanoyl Phosphatidylcholine; 3-sn-Phosphatidylcholine, 1,2-di(3,7,11,15-tetramethylhexadecanoyl)-; PC(16:0(3Me,7Me,11Me,15Me)/16:0(3Me,7Me,11Me,15Me)); 1,2-Bis(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Diphytanoylphosphatidylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, ethanol; forms liposomes in aqueous buffer
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.