Description

Dibutyryl Cyclic Gmp CAS NO 32266-35-6 is a cell-permeable, biologically stable analog of cyclic guanosine monophosphate (cGMP). This compound is a crucial research tool for studying intracellular signaling pathways, particularly those mediated by cGMP-dependent protein kinases (PKG). It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating cardiovascular function, smooth muscle relaxation, and neurological processes.

Application

• Biochemical Research: Used as a stable, membrane-permeable activator of cGMP-dependent protein kinases (PKG) in cell culture and in vitro studies.
• Cardiovascular Research: Investigates mechanisms of vasodilation, blood pressure regulation, and platelet aggregation inhibition.
• Neuroscience Studies: Explores roles in neuronal signaling, synaptic plasticity, and neuroprotection.
• Smooth Muscle Physiology: Studies relaxation mechanisms in vascular, bronchial, and gastrointestinal smooth muscle tissues.
• Pharmaceutical Development: Serves as a reference standard and tool compound in drug discovery programs targeting cGMP pathways.
• Cell Signaling Pathway Analysis: Used to elucidate downstream effects of nitric oxide (NO) and natriuretic peptide signaling.

Basic Information

Product Name	Dibutyryl Cyclic Gmp
CAS No.	32266-35-6
Molecular Formula	C₁₈H₂₅N₅O₉P
Molecular Weight	510.40 g/mol
Synonyms	N2,2'-O-Dibutyryl-guanosine 3',5'-cyclic monophosphate; N2,O2'-Dibutyryl-cGMP; Dibutyryl-cGMP; DB-cGMP; N2,2'-O-Dibutyryl-cyclic GMP; N2,O2'-Dibutyryl-3',5'-cyclic GMP sodium salt; Bt2cGMP; 2',O-Dibutyryl-3',5'-cyclic GMP
EINECS	Contact for details

Quality Control

Our Dibutyryl Cyclic Gmp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.