Description

Ancistrocladine is a naturally occurring isoquinoline alkaloid isolated from tropical lianas of the genus *Ancistrocladus*. This compound is of significant interest in pharmaceutical research due to its unique molecular structure and potent biological activities. It serves as a valuable reference standard and building block for researchers in drug discovery and development. Key industrial users include pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on antiviral, anticancer, and antiparasitic agent development.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of alkaloid-based drug candidates and natural product extracts via HPLC, LC-MS, or NMR.
• Drug Discovery Research: Acts as a lead compound or a pharmacophore model for synthesizing novel analogs with enhanced bioactivity and selectivity.
• Antiviral Agent Development: Investigated for its inhibitory activity against viruses such as HIV, making it a key compound in virology and antiviral therapy research.
• Anticancer Research: Studied for its cytotoxic properties against various cancer cell lines, supporting oncology and chemotherapy development programs.
• Antiparasitic Agent Research: Evaluated for potential efficacy against malaria and other parasitic diseases, contributing to tropical medicine research.
• Biochemical Tool Compound: Utilized in mechanistic studies to understand specific enzyme interactions and cellular pathways.
• Natural Product Chemistry: Serves as a benchmark compound for the isolation, identification, and structural elucidation of related alkaloids.
• Academic & Contract Research: Supplied to universities and CROs for fundamental pharmacological and phytochemical studies.

Basic Information

Product Name	Ancistrocladine
CAS No.	32221-59-3
Molecular Formula	C25H27NO4
Molecular Weight	405.49 g/mol
Synonyms	Ancistrocladine; Ancistrocladisine; (5aS,13bR)-5,6,13,13b-Tetrahydro-2,3,9,10-tetramethoxy-5H-isoindolo[2,1-a][3]benzazocine; Isoquinoline alkaloid from Ancistrocladus sp.
EINECS	Contact for details

Quality Control

Every batch of Ancistrocladine is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade materials. Comprehensive analytical characterization, including HPLC, NMR, and MS, is performed. Certificates of Analysis (COA) detailing purity, identification, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.