Description

Poly(2''-Deoxyadenyl-Thymidylic Acid) Sodium Salt is a synthetic oligonucleotide sodium salt, a key building block in molecular biology and genetic research. This compound is essential for applications requiring defined DNA sequences, such as primer synthesis, probe development, and structural studies. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in genomics, diagnostics, and therapeutic development.

Application

• Primer Synthesis: Used as a precise component for constructing PCR primers and sequencing primers.
• Nucleic Acid Probes: Serves as a fundamental unit in the development of labeled probes for hybridization assays (e.g., Southern blot, FISH).
• Structural Biology Studies: Employed in X-ray crystallography and NMR spectroscopy to investigate DNA structure and protein-DNA interactions.
• Therapeutic Oligonucleotide Research: Acts as a starting material or intermediate in the research and development of antisense oligonucleotides and other nucleic acid-based therapeutics.
• Molecular Diagnostics: Integral to the design and manufacture of components for diagnostic test kits targeting specific genetic sequences.
• Biochemical Reagent: Used as a substrate or standard in enzymatic assays involving polymerases, nucleases, and ligases.

Basic Information

Product Name	Poly(2''-Deoxyadenyl-Thymidylic Acid) Sodium Salt
CAS No.	31834-53-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(dA-dT) Sodium Salt; Poly(deoxyadenylic-deoxythymidylic) Acid Sodium Salt; Poly(dA-dT); Alternating dA-dT Copolymer; DNA Polymer (dA-dT); Poly(deoxyadenylate-deoxythymidylate); Poly(dAdT); Synthetic DNA Sodium Salt
EINECS	Contact for details

Quality Control

Our Poly(2''-Deoxyadenyl-Thymidylic Acid) Sodium Salt is produced and tested under stringent quality management systems. Each batch is analyzed to ensure high purity, correct sequence integrity, and consistent performance. Certificates of Analysis (COA) providing detailed specifications for purity, absorbance ratios, and endotoxin levels are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (UV-Vis)	Characteristic absorbance profile
Purity (HPLC)	≥ 95%
A260/A280 Ratio	1.8 - 2.0
Moisture Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.