Description

Undecaprenyl Diphosphate-(n-Acetylglucosaminyl)(1-4)-n-Acetylmuramoyl Pentapeptide is a critical lipid-linked intermediate in the biosynthesis of bacterial peptidoglycan. This specialized molecule is essential for researchers and developers focused on understanding and targeting bacterial cell wall assembly. It serves as a key substrate for studying the mechanism of action of antibiotics like bacitracin and vancomycin, and for high-throughput screening of novel antimicrobial agents. This compound is vital for biochemical research, enzymology studies, and drug discovery programs within the pharmaceutical and life sciences industries.

Application

• Biochemical Research: Essential substrate for in vitro studies of peptidoglycan biosynthesis enzymes, such as MurG and transglycosylases.
• Antibiotic Mechanism Studies: Used to investigate the inhibitory action of antibiotics (e.g., bacitracin, moenomycin) that target the lipid cycle of cell wall formation.
• Drug Discovery & Screening: Key component in high-throughput assays designed to identify novel inhibitors of bacterial cell wall synthesis for new antibiotic development.
• Enzymology: Serves as a defined substrate for kinetic and structural characterization of membrane-associated glycosyltransferases.
• Microbiology: Used in reconstitution experiments to study the complex process of cell wall assembly in model bacterial systems.
• Pharmaceutical Development: Supports target validation and lead optimization stages in anti-infective therapeutic programs.

Basic Information

Product Name	Undecaprenyl Diphosphate-(n-Acetylglucosaminyl)(1-4)-n-Acetylmuramoyl Pentapeptide
CAS No.	31587-66-3
Molecular Formula	C₁₀₀H₁₆₈N₈O₃₈P₂
Molecular Weight	~2150 g/mol (Contact for exact mass)
Synonyms	Lipid II (Bacterial); Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-pentapeptide; Park's Nucleotide (lipid-linked); UDP-MurNAc-pentapeptide:undecaprenyl phosphate N-acetylglucosaminyltransferase product; C55-PP-MurNAc-(GlcNAc)-pentapeptide; Bacoprenyl-diphospho-MurNAc-(GlcNAc)-pentapeptide
EINECS	Contact for details

Quality Control

Our Undecaprenyl Diphosphate-(n-Acetylglucosaminyl)(1-4)-n-Acetylmuramoyl Pentapeptide is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and assay is provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid/film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 90%
Assay (Enzymatic/Phosphorus)	≥ 85%
Solubility	Soluble in chloroform/methanol/water mixtures, DMSO (limited)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.