Description

Pregnanolone 3-β-D-Glucuronide is a crucial conjugated metabolite of the neurosteroid pregnanolone. This compound is of significant value in biochemical research and diagnostic development due to its role as a specific biomarker. It is primarily needed by pharmaceutical R&D laboratories, clinical research organizations, and manufacturers of in-vitro diagnostic (IVD) kits and reference standards.

Application

• Biomarker Research: Used as a reference standard in studies investigating neurosteroid metabolism and related endocrine pathways.
• Diagnostic Kit Development: Serves as a critical calibrator or control in the manufacturing of immunoassay kits for hormone level testing.
• Metabolite Identification: Employed in analytical method development (LC-MS/MS, HPLC) for the precise identification and quantification of steroid metabolites in biological matrices.
• Pharmacokinetic Studies: Essential for studying the absorption, distribution, metabolism, and excretion (ADME) profiles of pregnanolone and related synthetic analogs.
• Reference Standard Production: Supplied to certified reference material (CRM) producers for creating traceable standards used in clinical and forensic toxicology.

Basic Information

Product Name	Pregnanolone 3-β-D-Glucuronide
CAS No.	31329-54-1
Molecular Formula	C27H42O9
Molecular Weight	510.62 g/mol
Synonyms	3α-Hydroxy-5β-pregnan-20-one 3-glucuronide; 5β-Pregnan-3α-ol-20-one 3-β-D-Glucuronide; Pregnanolone Glucuronide; Allopregnanolone 3-Glucuronide; 3α-Hydroxy-5β-pregnan-20-one 3-β-D-Glucopyranosiduronic Acid; PDG; 5β-Pregnane-3α,20α-diol Glucuronide (related metabolite).
EINECS	Contact for details

Quality Control

Our Pregnanolone 3-β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.