Description

5'-Palmitoyl Cytarabine is a lipophilic prodrug derivative of the established antineoplastic agent Cytarabine. This chemical modification enhances the compound's cellular uptake and bioavailability, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the oncology and life sciences sectors for developing novel therapeutic formulations and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of advanced, liposome-encapsulated chemotherapeutic agents.
• Oncology Research: Used in preclinical studies to investigate prodrug strategies for improving the pharmacokinetic profile and efficacy of cytarabine.
• Drug Delivery Systems: Incorporated into lipid-based nanoparticle formulations (e.g., liposomes, micelles) for targeted cancer therapy.
• Bioconjugation Studies: Serves as a model compound for studying fatty acid conjugation to nucleoside analogs.
• API Development: Intermediate in the development of new Active Pharmaceutical Ingredients (APIs) with enhanced membrane permeability.

Basic Information

Product Name	5'-Palmitoyl Cytarabine
CAS No.	31088-06-9
Molecular Formula	C30H52N4O7
Molecular Weight	580.76 g/mol
Synonyms	N4-Palmitoyl Cytarabine; Cytarabine 5'-Palmitate; 1-β-D-Arabinofuranosylcytosine 5'-Palmitate; Cytosine Arabinoside 5'-Palmitate; Ara-C 5'-Palmitate; 5'-O-Palmitoyl-1-β-D-arabinofuranosylcytosine; Liposomal Cytarabine Derivative; Cytarabine Palmitoyl Ester
EINECS	Contact for details

Quality Control

Our 5'-Palmitoyl Cytarabine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.