Description

3A,7A-Dihydroxycholanoic Acid is a key dihydroxy bile acid derivative with significant biochemical relevance. This compound serves as a crucial intermediate in the synthesis of more complex bile acids and steroid-based pharmaceuticals, offering high purity for research and development applications. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on metabolic pathway studies and novel therapeutic agent development.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Biochemical Research: Used as a reference standard and reagent in studies of cholesterol metabolism, liver function, and bile acid biosynthesis pathways.
• Metabolite Analysis: Serves as an analytical standard in LC-MS and HPLC methods for quantifying bile acid profiles in biological samples.
• Enzymology Studies: Employed as a substrate to investigate the activity and kinetics of hepatic enzymes like cytochrome P450 and hydroxysteroid dehydrogenases.
• Cell Culture & In Vitro Studies: Applied in research models to study the effects of specific bile acids on cell signaling, apoptosis, and membrane dynamics.

Basic Information

Product Name	3A,7A-Dihydroxycholanoic Acid
CAS No.	30634-99-2
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	3α,7α-Dihydroxy-5β-cholan-24-oic Acid; 3α,7α-Dihydroxy-5β-cholanoic Acid; Chenodeoxycholic Acid Impurity; Dihydroxycholanoic Acid; 5β-Cholan-24-oic Acid-3α,7α-diol; 3α,7α-Dihydroxycholanic Acid; CDCA Related Compound
EINECS	Contact for details

Quality Control

Our 3A,7A-Dihydroxycholanoic Acid is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity suitable for research applications. Standard quality parameters include identity confirmation by spectroscopic methods and purity determination by chromatography. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.