Description

2,5-Dioxopyrrolidin-1-Yl Propanoate is a specialized active ester reagent widely used in organic synthesis and bioconjugation chemistry. This compound is valued for its high reactivity as an acylating agent, enabling efficient amide bond formation under mild conditions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors, particularly for peptide synthesis and the modification of biomolecules. The product is supplied with a CAS No. of 30364-55-7.

Application

• Peptide Synthesis: Acts as a key coupling reagent for the formation of amide bonds in solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Used for labeling proteins, antibodies, and other biomolecules with fluorescent dyes, drugs, or other functional probes.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for the synthesis of specialized polymers and hydrogels.
• Pharmaceutical Intermediates: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Used in surface modification and the creation of functionalized materials with specific chemical properties.

Basic Information

Product Name	2,5-Dioxopyrrolidin-1-Yl Propanoate
CAS No.	30364-55-7
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	Propanoic Acid, 2,5-Dioxo-1-pyrrolidinyl Ester; N-Hydroxysuccinimide Propionate; NHS Propionate; N-Succinimidyl Propanoate; 1-[(Propionyloxy)-2,5-pyrrolidinedione]; Succinimidyl Propionate; Propionic Acid N-Hydroxysuccinimide Ester; 30364-55-7
EINECS	Contact for details

Quality Control

Our 2,5-Dioxopyrrolidin-1-Yl Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.