Description

Butyrylcholine CAS NO 3922-86-9 is a choline ester and a synthetic analog of the neurotransmitter acetylcholine. This compound serves as a critical substrate for the enzyme butyrylcholinesterase (BChE), making it essential for biochemical research and diagnostic applications. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions studying cholinergic systems and enzyme kinetics.

Application

• Enzyme Substrate for Butyrylcholinesterase (BChE): Primary use as a specific substrate in enzymatic assays to measure BChE activity in research and clinical diagnostics.
• Biochemical Research: Investigation of cholinesterase enzyme kinetics, inhibition mechanisms, and structure-activity relationships.
• Diagnostic Reagent Manufacturing: A key raw material in the production of diagnostic kits for liver function tests and for monitoring exposure to organophosphate pesticides or nerve agents.
• Neuropharmacology Studies: Used in studies exploring the role of butyrylcholinesterase in neurodegenerative diseases such as Alzheimer's.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical and diagnostic laboratories.
• Toxicology Screening: Employed in assays designed to screen for compounds that inhibit cholinesterase activity.

Basic Information

Product Name	Butyrylcholine
CAS No.	3922-86-9
Molecular Formula	C9H20NO2+
Molecular Weight	174.26 g/mol (cation)
Synonyms	Butyrylcholine; Butanoylcholine; Butyroylcholine; 2-Butanoyloxyethyl(trimethyl)azanium; Choline butyrate ester; Butyrylcholine cation; NSC 32600; BChE substrate
EINECS	223-500-8

Quality Control

Our Butyrylcholine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by IR spectroscopy, purity assay by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and diagnostic-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.