Description

Butyrylcholine is a synthetic choline ester and a selective substrate for the enzyme butyrylcholinesterase (BChE). This compound is of significant value in biochemical and pharmacological research for studying cholinergic systems and enzyme kinetics. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and diagnostic manufacturers involved in neuroscience, toxicology, and the development of therapeutic agents for conditions like Alzheimer's disease.

Application

• Enzyme Substrate for Research: Primary substrate for the specific assay and kinetic study of butyrylcholinesterase (BChE) activity.
• Neuroscience & Pharmacology: Used in research models to investigate the role of BChE in the central and peripheral nervous systems and its interaction with various inhibitors.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical diagnostic kits for measuring pseudocholinesterase levels in human serum.
• Toxicology Studies: Employed in screening and evaluating the potency of organophosphate and carbamate pesticides, nerve agents, and their antidotes.
• Drug Discovery: Serves as a tool compound for high-throughput screening (HTS) campaigns aimed at discovering new BChE modulators for therapeutic applications.
• Biochemical Standard: Used as a reference standard for calibrating analytical instruments and validating assay methods in quality control laboratories.

Basic Information

Product Name	Butyrylcholine
CAS No.	3919-73-1
Molecular Formula	C9H20NO2+
Molecular Weight	174.26 g/mol (cation)
Synonyms	Butyrylcholine; Butanoylcholine; Butyroylcholine; Butyrylcholine cation; 2-Butanoyloxyethyl(trimethyl)azanium; NSC 209101; Butyrylcholine iodide (salt form common); Choline butyrate ester
EINECS	223-484-8

Quality Control

Our Butyrylcholine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.