Description

Triamcinolone 21-Acetate is a synthetic corticosteroid derivative, widely recognized for its potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of advanced pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of topical and injectable corticosteroid medications for treating various dermatological, ophthalmic, and inflammatory conditions.

Application

• Pharmaceutical API: Core ingredient in the manufacture of topical creams, ointments, and lotions for treating eczema, psoriasis, and dermatitis.
• Injectable Formulations: Used in the production of injectable suspensions for intra-articular or soft tissue administration to reduce inflammation.
• Ophthalmic Preparations: Key component in eye drops and ointments for managing inflammatory eye conditions.
• Veterinary Medicine: Employed in anti-inflammatory and anti-pruritic treatments for companion animals.
• Research & Development: Serves as a reference standard and building block in pharmacological research and new drug development.
• Compounding Pharmacy: Used by specialized pharmacies to prepare customized medication formulations.

Basic Information

Product Name	Triamcinolone 21-Acetate
CAS No.	3859-65-2
Molecular Formula	C26H33FO7
Molecular Weight	476.54 g/mol
Synonyms	Triamcinolone Acetate; 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate; 9α-Fluoro-16α-hydroxyprednisolone 21-acetate; Kenalog; Aristocort; Volon A; Triamcinolone 16α,17α-acetonide acetate (common misnomer, corrects to 21-acetate); Fluorotriamcinolone acetonide acetate (related compound reference)
EINECS	223-369-2

Quality Control

Our Triamcinolone 21-Acetate is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided with each batch, detailing results for identity, assay, purity, and specified impurities. We can support compliance with relevant pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.