Description

Glutathionesulfonic Acid CAS NO 3773-07-7 is a chemically modified derivative of the essential tripeptide glutathione, featuring a sulfonic acid group. This modification enhances its water solubility and alters its redox properties, making it a valuable biochemical tool and a potential precursor for advanced research compounds. It is primarily sought by researchers and developers in the fields of biochemistry, pharmaceutical development, and life sciences. This compound is utilized for studying enzyme mechanisms, oxidative stress pathways, and as a building block for novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving glutathione S-transferases (GSTs) and other redox-related enzymes.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor or model compound in the development of new drugs targeting oxidative stress, such as in neurodegenerative or inflammatory diseases.
• Proteomics & Cell Biology: Employed as a tool to modulate intracellular glutathione levels and study the effects on cell signaling, apoptosis, and detoxification pathways.
• Antioxidant Mechanism Studies: Acts as a modified antioxidant to investigate structure-activity relationships and the role of sulfonation in radical scavenging.
• Diagnostic Reagent Development: Potential use in formulating assay kits for measuring glutathione-related enzyme activity or oxidative stress markers.
• Reference Standard: Used as a high-purity analytical standard in HPLC or LC-MS methods for quality control and metabolic studies.

Basic Information

Product Name	Glutathionesulfonic Acid
CAS No.	3773-07-7
Molecular Formula	C10H17N3O8S2
Molecular Weight	371.39 g/mol
Synonyms	L-Glutathionesulfonic Acid; γ-Glutamylcysteinylglycine Sulfonic Acid; Glutathione Sulfonate; GSH Sulfonate; NSC 113236; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfoethyl]carbamoyl}butanoic Acid; Glutathione Sulphonic Acid; γ-L-Glutamyl-L-cysteinylglycine Sulfonic Acid
EINECS	Contact for details

Quality Control

Our Glutathionesulfonic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.