Description

1,2-Dioleoyl-Rac-Glycerol is a high-purity synthetic glyceride, specifically a diacylglycerol (DAG) with oleic acid as the fatty acid component. This compound serves as a critical intermediate and reference standard in lipid biochemistry and pharmaceutical research. It is essential for researchers and manufacturers developing advanced lipid-based drug delivery systems, such as liposomes and nanoemulsions, and for studying lipid metabolism. Industries that rely on this product include pharmaceutical R&D, nutraceutical formulation, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex phospholipids and other bioactive lipids for drug delivery applications.
• Lipid Research Standard: Used as a high-purity reference standard in analytical laboratories for chromatography (HPLC, GC) and mass spectrometry to study lipid profiles and metabolism.
• Biochemical Substrate: Employed in enzymatic studies, particularly for lipases and phospholipases, to investigate reaction mechanisms and kinetics.
• Liposome & Nanoemulsion Formulation: Acts as a component in the development of lipid nanoparticles (LNPs) and other colloidal carriers for enhancing drug solubility and targeted delivery.
• Nutraceutical Development: Investigated for use in functional food and dietary supplement formulations due to the bioactive properties of diacylglycerols.
• Cosmetic Ingredient: Utilized in high-end skincare formulations as an emollient and skin-conditioning agent.

Basic Information

Product Name	1,2-Dioleoyl-Rac-Glycerol
CAS No.	3738-74-7
Molecular Formula	C39H72O5
Molecular Weight	621.00 g/mol
Synonyms	1,2-Dioleoyl-rac-glycerol; rac-1,2-Dioleoylglycerol; Diolein (mixed isomer); 1,2-Di-(cis-9-octadecenoyl)-rac-glycerol; Glycerol 1,2-dioleate; DG(18:1/18:1/0:0); DAG 18:1; 1,2-Di-O-oleoyl-rac-glycerol
EINECS	223-110-6

Quality Control

Every batch of our 1,2-Dioleoyl-Rac-Glycerol is produced and analyzed under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation. For long-term storage, keep the container sealed in a cool, dry place. Allow the product to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
1,3-Dioleoyl-Rac-Glycerol (HPLC)	≤ 3.0%
Monoolein (HPLC)	≤ 1.0%
Free Fatty Acid (Titration)	≤ 1.0%
Peroxide Value	≤ 5.0 meq/kg
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.