Description

4-[Ethyl(Methyl)Amino]-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,6,10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide is a complex tetracycline-class antibiotic intermediate with significant synthetic utility. This compound matters as a crucial building block for advanced pharmaceutical research and development, particularly in the synthesis of novel antimicrobial agents. It is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in antibiotic development and chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel tetracycline and glycylcycline antibiotic derivatives.
• Antimicrobial Research: Used as a reference standard and starting material in the development of new antibacterial compounds targeting resistant pathogens.
• Chemical Synthesis: Serves as a complex chiral scaffold for medicinal chemistry programs exploring structure-activity relationships (SAR).
• Biochemical Studies: Employed in research investigating the mechanism of action and binding of tetracycline-class drugs to the bacterial ribosome.
• Process Development: Utilized in scaling up and optimizing synthetic routes for advanced antibiotic manufacturing.

Basic Information

Product Name	4-[Ethyl(Methyl)Amino]-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,6,10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide
CAS No.	3687-90-9
Molecular Formula	C₂₃H₂₈N₂O₉
Molecular Weight	476.48 g/mol
Synonyms	4-(Ethylmethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 4-[(Ethylmethyl)amino]-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline; Sancycline; 6-Demethyl-6-deoxytetracycline; Antibiotic U-24973A; 6-Methylene-5-oxytetracycline
EINECS	Contact for details

Quality Control

Our 4-[Ethyl(Methyl)Amino]-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,6,10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.