Description

Aldosterone 18-Glucuronide is a key conjugated metabolite of the mineralocorticoid hormone aldosterone. This compound is of significant importance in biochemical research and diagnostic applications due to its role as a primary urinary excretion product of aldosterone. It is essential for laboratories focused on endocrinology, hypertension research, and clinical diagnostics, particularly for developing and calibrating immunoassays. The product is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for studying aldosterone metabolism and mineralocorticoid pathways.
• Diagnostic Assay Development: Serves as a critical calibrator and control in the development of immunoassays (e.g., ELISA, RIA) for quantifying aldosterone levels in biological fluids.
• Clinical Endocrinology: Employed in research investigating disorders related to the renin-angiotensin-aldosterone system (RAAS), such as primary aldosteronism and hypertension.
• Pharmaceutical Analysis: Used in pharmacokinetic and drug metabolism studies for compounds that interact with aldosterone pathways.
• Quality Control in Diagnostics: Acts as a benchmark for ensuring the accuracy and precision of commercial diagnostic kits measuring aldosterone and its metabolites.
• Metabolite Profiling: A vital component in mass spectrometry-based metabolomics and steroid profiling studies.

Basic Information

Product Name	Aldosterone 18-Glucuronide
CAS No.	3604-86-2
Molecular Formula	C30H44O12
Molecular Weight	596.67 g/mol
Synonyms	Aldosterone 18-Glucuronide; Aldosterone 18-β-D-Glucopyranosiduronic Acid; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al 18→(O-β-D-Glucopyranosyluronic Acid); 18-Glucuronyl Aldosterone; Aldosterone 18-G; Aldosterone Glucuronide; Aldosterone-18-glucuronide
EINECS	Contact for details

Quality Control

Our Aldosterone 18-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.