Description

3Alpha-Hydroxy-5Beta-Androstan-17-One 3-Glucuronide is a specific glucuronide conjugate of a reduced androgen metabolite, serving as a crucial reference standard and biochemical intermediate. This compound is essential for research and development in endocrinology and analytical chemistry, providing a defined molecular entity for method validation and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions focused on steroid metabolism, hormone analysis, and biomarker discovery.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, LC-MS/MS) in drug metabolism and pharmacokinetics (DMPK) studies.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to glucuronidation pathways and steroid hormone metabolism.
• Diagnostic Development: Acts as a critical component in the development and quality control of immunoassays and clinical diagnostic kits for steroid hormone profiling.
• Metabolite Identification: Employed as an authentic standard for the definitive identification of phase II metabolites in biological samples during preclinical and clinical research.
• Academic Research: Used in university and institutional labs for fundamental studies on androgen biosynthesis, conjugation, and excretion mechanisms.
• Quality Control: Integral for the in-house QC of pharmaceutical products where monitoring of specific steroid conjugates is required.

Basic Information

Product Name	3Alpha-Hydroxy-5Beta-Androstan-17-One 3-Glucuronide
CAS No.	3602-09-3
Molecular Formula	C25H38O9
Molecular Weight	482.57 g/mol
Synonyms	Etiocholanolone Glucuronide; 3α-Hydroxy-5β-androstan-17-one 3-glucuronide; 5β-Androstan-3α-ol-17-one 3-glucuronide; Etiocholanolone 3-Glucuronide; 17-Oxo-5β-androstan-3α-yl β-D-Glucopyranosiduronic Acid; Androstane-3α,17β-diol-17-glucuronide (related); Steroid glucuronide reference standard
EINECS	Contact for details

Quality Control

Our 3Alpha-Hydroxy-5Beta-Androstan-17-One 3-Glucuronide is manufactured and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment (HPLC) and structural confirmation (NMR, MS), to ensure identity, potency, and consistency. Certificates of Analysis (COA) with batch-specific data are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.