Description

2-Deoxy-D-Glucose-6-Phosphate is a phosphorylated derivative of 2-deoxy-D-glucose, a key analog used to study cellular glucose metabolism. This compound is critical for researchers investigating the hexokinase reaction, glycolysis inhibition, and energy deprivation pathways in biological systems. It is primarily utilized in biochemical research, pharmaceutical development, and diagnostic applications where precise modulation of glucose metabolism is required.

Application

• Biochemical Research: Serves as a substrate analog and competitive inhibitor in enzymatic studies of hexokinase and glucose-6-phosphate dehydrogenase.
• Metabolic Pathway Analysis: Used to investigate glycolysis, the pentose phosphate pathway, and cellular energy homeostasis in vitro.
• Pharmaceutical Development: Employed in early-stage research for metabolic disorders and oncology, studying the Warburg effect and tumor cell metabolism.
• Diagnostic Reagent Manufacturing: A potential component in assay kits for measuring enzymatic activity in clinical and research laboratories.
• Cell Biology Studies: Applied to induce metabolic stress and study autophagy, apoptosis, and cellular response to energy depletion.

Basic Information

Product Name	2-Deoxy-D-Glucose-6-Phosphate
CAS No.	3573-50-0
Molecular Formula	C6H13O9P
Molecular Weight	260.14 g/mol
Synonyms	2-Deoxyglucose-6-phosphate; 2-DG-6-P; 2-Deoxy-D-glucose 6-(dihydrogen phosphate); 6-O-Phosphono-2-deoxy-D-glucose; D-2-Deoxyglucose 6-phosphate; 2-Deoxy-D-arabino-hexose 6-phosphate
EINECS	Contact for details

Quality Control

Our 2-Deoxy-D-Glucose-6-Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency for research applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (5% solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.