Description

Anabaseine is a naturally occurring alkaloid and a potent nicotinic acetylcholine receptor (nAChR) agonist. This compound serves as a critical research chemical and a valuable synthetic intermediate in the development of novel pharmaceuticals and agrochemicals. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neuroscience, medicinal chemistry, and crop protection solutions.

Application

• Neuroscience Research: A key tool compound for studying the structure and function of nicotinic acetylcholine receptors (nAChRs) in the central and peripheral nervous systems.
• Medicinal Chemistry: Acts as a versatile scaffold and lead structure for the synthesis of novel drug candidates targeting cognitive disorders, pain, and addiction.
• Agrochemical Development: Investigated as a precursor or model compound for creating new classes of insecticides and nematicides that target specific neuronal pathways in pests.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro assays to identify and characterize new nAChR modulators.
• Chemical Synthesis: Employed as a sophisticated chiral building block for the total synthesis of complex natural products and other alkaloids.

Basic Information

Product Name	Anabaseine
CAS No.	3471-05-4
Molecular Formula	C10H12N2
Molecular Weight	160.22 g/mol
Synonyms	3-(2,3'-Bipyridin-6'-yl)-2-propen-1-amine; 3-(1,2,3,6-Tetrahydro-2,3'-bipyrid-6'-yl)pyridine; 2-(3-Pyridyl)-1,2,3,6-tetrahydropyridine; Nemertelline; Anabasine, dihydro-; (E)-3-(2,3'-Bipyridin-6'-yl)acrylamine
EINECS	Contact for details

Quality Control

Our Anabaseine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical services are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.